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phenobarbital will decrease the extent or result of stiripentol by affecting hepatic enzyme CYP1A2 metabolism. Avoid or Use Alternate Drug. If struggling to keep away from coadministration of stiripentol with strong CYP1A2 inducers, increase stiripentol dose.Monitor Closely (1)somatropin will lessen the extent or effect of phenobarbital by impactin